Innovative dermocosmetics research boosted with gut and gut-brain axis
Make major scientific breakthroughs in your innovative dermocosmetics research
When the skin is subjected to stress (oxidative agents, exacerbated inflammation, pollution, etc.), the exacerbated release of NO and H2O2 leads to alterations in vital biological processes, which damage skin balance (through lipid peroxidation, irreversible DNA damage, mitochondrial dysfunction, dysruption of the barrier function, etc.).
That is why at Enterosys we have developed an innovative amperometry-based method for the ultrasensitive detection of reactive oxygen species (NO and H2O2) in real time, which can be used to predict the antioxidant capacity of new skin treatment compounds. Number of scientific studies have demonstrated the key role of NO and H2O2 in regulating the skin’s balance. Released in small quantities by the skin barrier cells, these mediators are involved in the essential processes which maintain optimal skin condition and health (cell renewal, respiration, scarring, permeability, melanogenesis, cell communication, etc.).
Challenge your dermocosmetic molecules with the expert on the gut and gut-organ axis!
Enterosys offers a holistic approach for efficacy testing by embracing the digestive sphere and the inter-organ communication to develop your portfolio of ingredients, molecules and future assets.
We accompany your innovation process by designing and conducting experimental protocols adapted to the development objectives of your dermocosmetic pipeline. Using our gut-organ expertise, we offer a wide range of tests providing you with new opportunities for differentiation.
GUT AND GUT-ORGAN PRECLINICAL STUDIES BOOST THE DEVELOPMENT OF YOUR MOLECULES
ENTEROSYS IS A CRO ROOTED IN THE GUT TO SUPPORT INNOVATIVE dermocosmetics RESEARCH
Enterosys offers rapid and innovative protocols for the analysis of physiological parameters in real time. Our approaches allow you to save time and costs in the development of your therapeutics to quickly position or reposition your assets. We help researchers to advance science and improve precision health much faster.
Our holistic gut-organ approach demonstrates the beneficial effects of molecules of interest and may also detect potential side effects on other organs very early in the development process. Our cutting-edge expertise allow you to leverage your molecules and to de-risk innovation.
White paper ENTEROSYS
« GUT IS THE LINK »
Our first white paper is now available !
Get inside the head of our co-founder Claude Knauf.
Come discover his background, his key dates, how he got the gut feeling and the link between enteric neurons and glycemic control as well as other health related areas.
OUR KEY SCIENTIFIC FINDINGS ABOUT THE GUT
Cell&Soft & Enterosys combine their expertise
Enterosys provides in vitro models closer to physiology for dermo cosmetic applications.
Enterosys analyzes the efficacy of dermocosmetic assets.
The preclinical services platform SkinObs dedicated to dermocosmetics describes Enterosys’ innovative approach to evaluate the antioxidant capacity of active ingredients
Do you have a question about the contribution of gut models to your preclinical studies and innovation portfolio ?
Our team of experts will be delighted to answer all of your questions. We guide you in the design of an optimized protocol to meet your objectives and add value to your molecules with quick and concrete solutions.