Preclinical studies
in gut & gut brain
for therapies of tomorrow
Enterosys is a CRO scientifically rooted
in the gut and inter-organ communication
We believe that gut and the gut-brain axis play a central role in lifelong health. The specialized expertise of our Contract Research Organization (CRO) enables you to make major scientific breakthroughs in the discovery and valuation of your therapeutic active ingredients.
At the heart of a holistic health approach, gut is the cornerstone of our preclinical expertise. Leveraging innovative technologies in integrated physiology, ENTEROSYS specializes in the preclinical evaluation of compounds in the overall digestive sphere, particularly the gut and its peripheral organs.
“You take the red pill; you stay in wonderland, and we show you how deep the rabbit-hole goes”
GUT & GUT BRAIN axis, A MAJOR ROLE IN HEALTH DISORDERS AND DISEASES
Gastrointestinal
disorders & diseases
Neurodegenerative
disorders & diseases
Metabolic
disorders & diseases
Dermatological
disorders & diseases
Challenge your molecules using our gut & gut-organs models
Custom preclinical models
Enterosys provides you with the required support in the design and development of new models. Our R&D expertise allows us to meet your most demanding objectives. Guided by a unique innovation management process, we adapt to your specific needs and offer you a real opportunity for differentiation.
Validated preclinical models
Enterosys brings you a complete and innovative offer of preclinical protocols based on validated in vitro and in vivo efficacy tests. We provide you with a wide range of efficiency tests and smart solutions to accelerate the development of your compounds and position your assets in the following areas:
- Digestive sphere
- Gut-Brain axis
- Gut-Adipose tissue axis
- Gut-Liver axis
- Gut-Skin axis
- Gut-Pancreas axis
At the cutting edge of
preclinical study
At the forefront of scientific research on the gut and gut-organ axis, our team brings you a new and disruptive approach to reveal the potential of your molecules. Our CRO addresses human and animal health, nutraceuticals, dermocosmetic products, feed and food industries.
Preclinical studies of tomorrow’s health solutions:
Pharmaceuticals
Nutraceuticals
Dermocosmetics
Food & Feed
White paper ENTEROSYS
« GUT IS THE LINK »
Our first white paper is now available !
Get inside the head of our co-founder Claude Knauf.
Come discover his background, his key dates, how he got the gut feeling and the link between enteric neurons and glycemic control as well as other health related areas.
Our key scientific findings about the gut
Enteric neurons for functional applications in health care
In the intestine, gut distension and nutrients are detected by mechanoreceptors and chemoreceptors, respectively. The activation of these receptors sends an afferent nervous message to the hypothalamus in the brain. In turn, the hypothalamus controls the glucose entry in tissues, and thus glycemia.
Enteric neurons and glycemia control
In the intestine, gut distension and nutrients are detected by mechanoreceptors and chemoreceptors, respectively. The activation of these receptors sends an afferent nervous message to the hypothalamus in the brain. In turn, the hypothalamus controls the glucose entry in tissues, and thus glycemia.
The enteric nervous system is our second brain
The enteric nervous system (ENS), referred to as the “second brain,” is an extensive network of different cell types located along the digestive tract.
Do you have a question about the contribution of gut models in your innovative research ?
Our team of experts will be delighted to answer all of your questions. We guide you in the design of an optimized protocol to meet your objectives and add value to your molecules with quick and concrete solutions.