Innovative nutraceutical research boosted with gut and gut-brain axis 

Make major scientific breakthroughs in your innovative nutraceutical research

Enterosys relies on a highly qualified team and state-of-the-art technical platform to evaluate the efficacy and toxicity of your product candidates in both in vitro and / or in vivo models. We offer efficacy tests that take into account the digestive system and inter-organ communication to develop your nutraceutical leads (ingredients, prebiotics or probiotics). Our holistic approach allows you to develop tomorrow’s preventive medicines.

We accompany you during your innovation process. According to your needs, we design and perform the experimental protocols adapted to the development objectives of your nutraceutical pipeline. To achieve this, we offer a wide range of tests which provide real opportunities for differentiation:

  • Screening of potential nutraceutical leads
  • Improvement of lead profiling and selection
  • Comparison of various compounds in different organs
  • Characterization and consolidation of  preventive effects
  • Characterization and consolidation of mechanisms of action
  • Repositioning of your compound

 

CRO for Nutraceuticals

Challenge your ingredients with the expert on the gut and the gut-organ axis!

New legislation, patent expirations and rising healthcare costs are demanding decisive changes in the global nutraceutical industry. You evolve in a very competitive environment, and you need smart solutions?

Enterosys offers rapid and innovative protocols to analyze physiological parameters in real time. Our approaches save time and costs in the development of your nutraceutics to quickly position or reposition your assets and prevent of risk factors. We help researchers to advance the science of precision health.

GUT AND GUT-ORGAN PRECLINICAL STUDIES BOOST THE DEVELOPMENT OF YOUR MOLECULES

ENTEROSYS IS A CRO ROOTED IN THE GUT TO SUPPORT INNOVATIVE NUTRACEUTICAL RESEARCH

Enterosys offers rapid and innovative protocols for the analysis of physiological parameters in real time. Our approaches allow you to save time and costs in the development of your therapeutics to quickly position or reposition your assets. We help researchers to advance science and improve precision health much faster.

Our holistic gut-organ approach demonstrates the beneficial effects of molecules of interest and may also detect potential side effects on other organs very early in the development process. Our cutting-edge expertise allows you to leverage your molecules and to de-risk innovation.

OUR KEY SCIENTIFIC FINDINGS ABOUT THE GUT

Targeting our second brain using prebiotics

Targeting our second brain using prebiotics

The discovery of intestinal actors, such as enterosynes, able to modulate the ENS-induced duodenal contraction is an innovative approach. Among all the intestinal factors, the understanding of the role of gut microbes in controlling glycaemia remains a major target. For instance, we researched and demonstrated how the modulation of gut microbiota by prebiotics could permit the identification of novel enterosynes.

How does the gut microbiota interact with our second brain?

How does the gut microbiota interact with our second brain?

Currently, the gut is considered a primary site for the development of pathologies that modify brain functions such as neurodegenerative (Parkinson’s, Alzheimer’s, etc.) and metabolic (type 2 diabetes, obesity, etc.) disorders. Deciphering the mode of interaction between microbiota and the brain is a real original option to prevent (and maybe treat in the future) the establishment of gut-brain disfunctions and associated pathologies.

Camu camu and its applications in nutraceutics

Camu camu and its applications in nutraceutics

The Amazonian forests are home to a shrub, the camu-camu, whose fruit could be of great help in the fight against obesity and metabolic diseases. This is described in our latest study published with the A-Mansia R&D team in the journal Metabolites.

Do you have a question about the contribution of gut models to your preclinical studies and innovation portfolio ?

Our team of experts will be delighted to answer all of your questions. We guide you in the design of an optimized protocol to meet your objectives and add value to your molecules with quick and concrete solutions.