Pharma innovative research boosted with gut and gut-brain axis
Make major scientific breakthroughs in your innovative pharma research
Thanks to our holistic approach on the gut and gut-brain axis, we accompany your innovation process by designing and implementing experimental protocols adapted to your pharmaceutical objectives and development pipeline. To that end, we use our expertise to offer a wide range of tests to provide you with real differentiation opportunities:
- Screening of potential assets
- Improvement of lead profiling and selection
- Comparison of various drug candidates in different organs
- Characterization and consolidation of mechanisms of action
- Characterization and consolidation of therapeutics effects
- Repositioning of your compounds
Reveal the potential of your pharmaceutical leads thanks to the gut and the gut-organ axis!
New legislation, patent expiration and rising healthcare costs are demanding decisive changes in the global pharmaceutical industry.
Your companies evolve in a very competitive environment. New and disruptive approaches are needed to pursue a holistic medical approach which integrates the digestive sphere and its impacts on the related peripheral organs.
Gut and gut-organ preclinical studies boost the development of your molecules
Enterosys is a CRO rooted in the gut to support innovative pharma research
Enterosys offers rapid and innovative protocols for the analysis of physiological parameters in real time. Our approaches allow you to save time and costs in the development of your therapeutics to quickly position or reposition your assets. We help researchers to advance science and improve precision health much faster.
Our holistic gut-organ approach demonstrates the beneficial effects of molecules of interest and may also detect potential side effects on other organs very early in the development process. Our cutting-edge expertise allow you to leverage your molecules and to de-risk innovation.
White paper ENTEROSYS
« GUT IS THE LINK »
Our first white paper is now available !
Get inside the head of our co-founder Claude Knauf.
Come discover his background, his key dates, how he got the gut feeling and the link between enteric neurons and glycemic control as well as other health related areas.
OUR KEY SCIENTIFIC FINDINGS ABOUT THE GUT
Enteric neurons for functional applications in health care
In the intestine, gut distension and nutrients are detected by mechanoreceptors and chemoreceptors, respectively. The activation of these receptors sends an afferent nervous message to the hypothalamus in the brain. In turn, the hypothalamus controls the glucose entry in tissues, and thus glycemia.
Enteric neurons and glycemia control
In the intestine, gut distension and nutrients are detected by mechanoreceptors and chemoreceptors, respectively. The activation of these receptors sends an afferent nervous message to the hypothalamus in the brain. In turn, the hypothalamus controls the glucose entry in tissues, and thus glycemia.
The enteric nervous system is our second brain
The enteric nervous system (ENS), referred to as the “second brain,” is an extensive network of different cell types located along the digestive tract.